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مرکز نوآوری سلول‌های بنیادی و پزشکی بازساختی

دانشگاه علوم پزشکی تهران

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FDA Approves CAR-T Cell Therapy for Diffuse Large B-Cell Lymphoma

FDA Approves CAR-T Cell Therapy for Diffuse Large B-Cell Lymphoma

The Food and Drug Administration (FDA) approved Kymriah (tisagenlecleucel) ? a CAR-T cell therapy ? for the treatment of adult patients who have relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who have relapsed or are ineligible for an autologous stem cell transplant (ASCT).

Scientists improve DNA transfer in gene therapy

Scientists improve DNA transfer in gene therapy

. By using this method, scientists from the German Primate Center (DPZ) __ Leibniz Institute for Primate Research have discovered a quicker and more efficient treatment for the cells.

$11.6 Million NIH Grant Supports Temple Researchers? Exploration of New Cell-Free Stem Cell-Based Possibilities in Heart Repair

$11.6 Million NIH Grant Supports Temple Researchers? Exploration of New Cell-Free Stem Cell-Based Possibilities in Heart Repair

The incidence of heart disease is on the rise, and new therapeutic strategies are needed. Approaches based on stem cells, which can potentially preserve or even regenerate heart muscle cells damaged by ischemia ? a hallmark of heart disease ? are especially promising. Now, thanks to an $11.6-Million Program Project Grant (PPG) from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) under award number P01HL134608, scientists at the Lewis Katz School of Medicine at Temple University (LKSOM) are poised to explore new possibilities in stem cell-based treatments for heart repair and regeneration.

Cancer ?vaccine? eliminates tumors in mice

Cancer ?vaccine? eliminates tumors in mice

Injecting minute amounts of two immune-stimulating agents directly into solid tumors in mice can eliminate all traces of cancer in the animals, including distant, untreated metastases, according to a study by researchers at the Stanford University School of Medicine.

What?s Next For CAR T: The Potential of Engineering Immune Cells to Treat Cancer

What?s Next For CAR T: The Potential of Engineering Immune Cells to Treat Cancer

It is not often that an entirely new, effective, class of therapy is discovered, especially in a disease as difficult to treat as cancer. It is even less common that a completely new therapeutic is effective in a large majority of patients right from the start. But chimeric antigen receptor T cell therapy?CAR T-cell therapy? is anything but typical

Lab-made ?mini organs? helping doctors treat cystic fibrosis

Lab-made ?mini organs? helping doctors treat cystic fibrosis

Els van der Heijden, who has cystic fibrosis, was finding it ever harder to breathe as her lungs filled with thick, sticky mucus. Despite taking more than a dozen pills and inhalers a day, the 53-year-old had to stop working and scale back doing the thing she loved best, horseback riding...

First implants derived from stem cells to ?cure? type 1 diabetes

First implants derived from stem cells to ?cure? type 1 diabetes

Last week, two people with type 1 diabetes became the first to receive implants containing cells generated from embryonic stem cells to treat their condition. The hope is that when blood sugar levels rise, the implants will release insulin to restore them to normal.

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